Efficient ecofriendly synthesis of pyrazole acryloyl analogs by amino acid catalysis

被引：8

作者：

Chaudhry, Faryal ^{[1
,2
]}

Asif, Nadia ^{[1
]}

Shafqat, Syed Salman ^{[3
]}

Khan, Amir Azam ^{[3
]}

Munawar, Munawar Ali ^{[1
]}

Khan, Misbahul Ain ^{[1
,4
]}

机构：

[1] Univ Punjab, Inst Chem, Lahore 54590, Pakistan

[2] Kinnaird Coll Women, Dept Chem, Lahore, Pakistan

[3] Univ Malaysia Sarawak, Dept Mech & Mfg Engn, Fac Engn, Sarawak, Malaysia

[4] Islamia Univ Bahawalpur, Dept Chem, Bahawalpur, Pakistan

来源：

SYNTHETIC COMMUNICATIONS | 2016年 / 46卷 / 08期

关键词：

Active methylenes; arylidenes; glycine; Knoevenagel condensation; pyrazole-3-carbaldehyde; KNOEVENAGEL CONDENSATION; IONIC LIQUID; MALONIC-ACID; DRY MEDIA; ALDEHYDES; ZEOLITE; GREEN;

D O I：

10.1080/00397911.2016.1164863

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

An easy and effective green approach of Knoevenagel condensation and arylidene formation with the substrates involves pyrazole-3-carbaldehydes and active methylenes under catalytic action of glycine (the simplest amino acid) in dimethylsulfoxide. These reactions were successfully carried out at room temperature. [GRAPHICS] .

引用

页码：701 / 709

页数：9

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