Complex regional pain syndrome

被引：140

作者：

Birklein, F ^{[1
]}

机构：

[1] Univ Mainz, Neurol Klin, D-55101 Mainz, Germany

来源：

JOURNAL OF NEUROLOGY | 2005年 / 252卷 / 02期

关键词：

complex regional pain syndrome (CRPS); sympathetically maintained pain (SMP); neurogenic inflammation; neuroplasticity; physical therapy;

D O I：

10.1007/s00415-005-0737-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Complex regional pain syndrome (CRPS) may develop after limb trauma and is characterized by pain, sensory-motor and autonomic symptoms. Most important for the understanding of the pathophysiology of CRPS are recent results of neurophysiological research. Major mechanism for CRPS symptoms, which might be present subsequently or in parallel during the course of CRPS, are trauma-related cytokine release, exaggerated neurogenic inflammation, sympathetically maintained pain and cortical reorganisation in response to chronic pain (neuroplasticity). The recognition of these mechanisms in individual CRPS patients is the prerequisite for a mechanism-oriented treatment.

引用

收藏

页码：131 / 138

页数：8

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