Nickel-Catalyzed Cross-Coupling of Aryl Phosphates with Arylboronic Acids

被引：99

作者：

Chen, Hu ^{[1
,2
]}

Huang, Zhongbin ^{[1
,2
]}

Hu, Xiaoming ^{[1
,2
]}

Tang, Guo ^{[1
,2
,4
]}

Xu, Pengxiang ^{[1
,2
]}

Zhao, Yufen ^{[1
,2
,3
]}

Cheng, Chien-Hong ^{[4
]}

机构：

[1] Xiamen Univ, Coll Chem & Chem Engn, Dept Chem, Xiamen 361005, Fujian, Peoples R China

[2] Xiamen Univ, Coll Chem & Chem Engn, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Fujian, Peoples R China

[3] Tsinghua Univ, Minist Educ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China

[4] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 07期

关键词：

TEMPERATURE SUZUKI-MIYAURA; CARBON-CARBON BONDS; C-O ACTIVATION; BORONIC ACIDS; ALKENYL PHOSPHATES; ORGANOBORON COMPOUNDS; GRIGNARD-REAGENTS; ENOL ETHERS; ESTERS; ALKYNES;

D O I：

10.1021/jo2000034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Suzuki-Miyaura cross-coupling of aryl phosphates using Ni(PCy(3))(2)Cl(2) as an inexpensive, bench-stable catalyst is described. Broad substrate scope and high efficiency are demonstrated by the syntheses of more than 40 biaryls and by constructing complex organic molecules. The poor reactivity of aryl phosphates relative to aryl halides is successfully employed to construct polyarenes by selective cross-coupling using Pd and Ni catalysts.

引用

页码：2338 / 2344

页数：7