DNA as a Versatile Chemical Component for Catalysis, Encoding, and Stereocontrol

被引:186
作者
Silverman, Scott K. [1 ]
机构
[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
catalysis; directed evolution; DNA; encoding; stereocontrol; PEPTIDE NUCLEIC-ACID; TEMPLATED ORGANIC-SYNTHESIS; DIELS-ALDERASE RIBOZYME; IN-VITRO SELECTION; DIVALENT METAL-IONS; DIRECTED EVOLUTION; ACTIVE-SITE; RATIONAL DESIGN; CLEAVING DNA; ARTIFICIAL METALLOENZYMES;
D O I
10.1002/anie.200906345
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Beyond biological DNA : Chemists are exploiting DNA for interesting applications as a catalyst, encoding component, and stereocontrol element. Each of these chemical applications takes advantage of a distinct subset of DNA's properties in ways not known in nature. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:7180 / 7201
页数:22
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