Solving the FYVE domain-PtdIns(3)P puzzle

被引：13

作者：

Driscoll, PC

机构：

[1] UCL, Dept Biochem & Mol Biol, London WC1E 6BT, England

[2] Ludwig Inst Canc Res, London W1W 7BS, England

来源：

NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 04期

关键词：

D O I：

10.1038/86144

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent crystallographic analyses of membrane-tethering FYVE finger domains from proteins involved in the regulation of endocytic vesicle trafficking have led to conflicting views of the precise nature of the contacts formed with the specific phospholipid ligand. New NMR data obtained for ligand-bound forms of a FYVE domain help resolve the atomic details of this interaction.

引用

页码：287 / 290

页数：4

共 16 条

[1] Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains
Burd, CG
Emr, SD
[J]. MOLECULAR CELL, 1998, 2 (01) : 157 - 162
[2] Phosphoinositides in membrane traffic
Corvera, S
D'Arrigo, A
Stenmark, H
[J]. CURRENT OPINION IN CELL BIOLOGY, 1999, 11 (04) : 460 - 465
[3] Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes - Role of conserved residues
Gaullier, JM
Ronning, E
Gillooly, DJ
Stenmark, H
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (32) : 24595 - 24600
[4] FYVE fingers bind Ptdins(3)P
Gaullier, JM
Simonsen, A
D'Arrigo, A
Bremnes, B
Stenmark, H
Aasland, R
[J]. NATURE, 1998, 394 (6692) : 432 - 433
[5] Structural mechanism of endosome docking by the FYVE domain
Kutateladze, T
Overduin, M
[J]. SCIENCE, 2001, 291 (5509) : 1793 - 1796
[6] Phosphatidylinositol 3-phosphate recognition by the FYVE domain
Kutateladze, TG
Ogburn, KD
Watson, WT
de Beer, T
Emr, SD
Burd, CG
Overduin, M
[J]. MOLECULAR CELL, 1999, 3 (06) : 805 - 811
[7] The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding - Critical role of this dual interaction for endosomal localization
Lawe, DC
Patki, V
Heller-Harrison, R
Lambright, D
Corvera, S
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (05) : 3699 - 3705
[8] Signalling through phosphoinositide 3-kinases: the lipids take centre stage
Leevers, SJ
Vanhaesebroeck, B
Waterfield, MD
[J]. CURRENT OPINION IN CELL BIOLOGY, 1999, 11 (02) : 219 - 225
[9] Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction
Mao, YX
Nickitenko, A
Duan, XQ
Lloyd, TE
Wu, MN
Bellen, H
Quiocho, FA
[J]. CELL, 2000, 100 (04) : 447 - 456
[10] Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p
Misra, S
Hurley, JH
[J]. CELL, 1999, 97 (05) : 657 - 666

← 1 2 →