The phosphoinositide-3-OH-kinase-related kinases of Arabidopsis thaliana

被引：29

作者：

Templeton, GW ^{[1
]}

Moorhead, GBG ^{[1
]}

机构：

[1] Univ Calgary, Dept Biol Sci, Calgary, AB T2N 1N4, Canada

来源：

EMBO REPORTS | 2005年 / 6卷 / 08期

关键词：

phosphoinositide-3-OH-kinase-related kinases; TOR (target of rapamycin); ATM (ataxia-telangiectasia mutated); ATR (ATM and RAD3-related); TRRAP (transactivation/transformation-domain-associated; protein);

D O I：

10.1038/sj.embor.7400479

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The phosphoinositide-3-OH-kinase-related kinases (PIKKs) are atypical protein kinases exclusive to eukaryotes. They mediate the cellular response to a range of stresses, including genome and RNA surveillance and availability of nutrients for growth. Orthologues of five out of the six PIKK family members are present in plant genomes. Recent studies in plant PIKKs have revealed features unique to, and in common with, other PIKKs. This review summarizes the basic knowledge of these proteins in mammals and yeast in comparison with what is known for Arabidopsis and other plants.

引用

页码：723 / 728

页数：6

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