Breast EIT using a new projected image reconstruction method with multi-frequency measurements

被引:29
作者
Lee, Eunjung [1 ]
Ts, Munkh-Erdene [1 ]
Seo, Jin Keun [1 ]
Woo, Eung Je [2 ]
机构
[1] Yonsei Univ, Dept Computat Sci & Engn, Seoul 120749, South Korea
[2] Kyung Hee Univ, Dept Biomed Engn, Gyeonggi Do, South Korea
基金
新加坡国家研究基金会;
关键词
breast EIT; projected image reconstruction method; multifrequency measurements; ELECTRICAL-IMPEDANCE TOMOGRAPHY; ELECTRODE ARRAYS; CANCER DETECTION; HUMAN HEAD; SYSTEM; DIFFERENCE; ALGORITHM; SPECTROSCOPY; FEASIBILITY; VALIDATION;
D O I
10.1088/0967-3334/33/5/751
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
We propose a new method to produce admittivity images of the breast for the diagnosis of breast cancer using electrical impedance tomography (EIT). Considering the anatomical structure of the breast, we designed an electrode configuration where current-injection and voltage-sensing electrodes are separated in such a way that internal current pathways are approximately along the tangential direction of an array of voltage-sensing electrodes. Unlike conventional EIT imaging methods where the number of injected currents is maximized to increase the total amount of measured data, current is injected only twice between two pairs of current-injection electrodes attached along the circumferential side of the breast. For each current injection, the induced voltages are measured from the front surface of the breast using as many voltage-sensing electrodes as possible. Although this electrode configuration allows us to measure induced voltages only on the front surface of the breast, they are more sensitive to an anomaly inside the breast since such an injected current tends to produce a more uniform internal current density distribution. Furthermore, the sensitivity of a measured boundary voltage between two equipotential lines on the front surface of the breast is improved since those equipotential lines are perpendicular to the primary direction of internal current streamlines. One should note that this novel data collection method is different from those of other frontal plane techniques such as the x-ray projection and T-scan imaging methods because we do not get any data on the plane that is perpendicular to the current flow. To reconstruct admittivity images using two measured voltage data sets, a new projected image reconstruction algorithm is developed. Numerical simulations demonstrate the frequency-difference EIT imaging of the breast. The results show that the new method is promising to accurately detect and localize small anomalies inside the breast.
引用
收藏
页码:751 / 765
页数:15
相关论文
共 34 条
[1]   Validation of weighted frequency-difference EIT using a three-dimensional hemisphere model and phantom [J].
Ahn, Sujin ;
Oh, Tong In ;
Jun, Sung Chan ;
Seo, Jin Keun ;
Woo, Eung Je .
PHYSIOLOGICAL MEASUREMENT, 2011, 32 (10) :1663-1680
[2]   T-Scan electrical impedance imaging system for anomaly detection [J].
Ammari, H ;
Kwon, O ;
Seo, JK ;
Woo, EJ .
SIAM JOURNAL ON APPLIED MATHEMATICS, 2004, 65 (01) :252-266
[3]   The T-SCAN™ technology:: electrical impedance as a diagnostic tool for breast cancer detection [J].
Assenheimer, M ;
Laver-Moskovitz, O ;
Malonek, D ;
Manor, D ;
Nahaliel, U ;
Nitzan, R ;
Saad, A .
PHYSIOLOGICAL MEASUREMENT, 2001, 22 (01) :1-8
[4]  
Bujnowski A, 2007, IFMBE PROC, V17, P396
[5]   A 3D electrical impedance tomography (EIT) system for breast cancer detection [J].
Cherepenin, V ;
Karpov, A ;
Korjenevsky, A ;
Kornienko, V ;
Mazaletskaya, A ;
Mazourov, D ;
Meister, D .
PHYSIOLOGICAL MEASUREMENT, 2001, 22 (01) :9-18
[6]   Three-dimensional EIT imaging of breast tissues: System design and clinical testing [J].
Cherepenin, VA ;
Karpov, AY ;
Korjenevsky, AV ;
Kornienko, VN ;
Kultiasov, YS ;
Ochapkin, MB ;
Trochanova, OV ;
Meister, JD .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2002, 21 (06) :662-667
[7]   A reconstruction algorithm for breast cancer imaging with electrical impedance tomography in mammography geometry [J].
Choi, Myoung Hwan ;
Kao, Tzu-Jen ;
Isaacson, David ;
Saulnier, Gary J. ;
Newell, Jonathan C. .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2007, 54 (04) :700-710
[8]   Experimental assessment of phase magnitude imaging in multifrequency EIT by simulation and saline tank studies [J].
Fitzgerald, A ;
Holder, D ;
Griffiths, H .
ELECTRICAL BIOIMPEDANCE METHODS: APPLICATIONS TO MEDICINE AND BIOTECHNOLOGY, 1999, 873 :381-387
[9]   The dielectric properties of biological tissues .1. Literature survey [J].
Gabriel, C ;
Gabriel, S ;
Corthout, E .
PHYSICS IN MEDICINE AND BIOLOGY, 1996, 41 (11) :2231-2249
[10]   SPECIFIC RESISTANCE OF BIOLOGICAL MATERIAL-A COMPENDUM OF DATA FOR BIOMEDICAL ENGINEER AND PHYSIOLOGIST [J].
GEDDES, LA ;
BAKER, LE .
MEDICAL & BIOLOGICAL ENGINEERING, 1967, 5 (03) :271-&