Identification of a progenitor of the CTX-M-9 group of extended-spectrum β-lactamases from Kluyvera georgiana isolated in Guyana

被引：92

作者：

Olson, AB

Silverman, M

Boyd, DA

McGeer, A

Willey, BM

Pong-Porter, V

Daneman, N

Mulvey, MR

机构：

[1] Natl Microbiol Lab, Winnipeg, MB R3E 3R2, Canada

[2] Univ Manitoba, Winnipeg, MB, Canada

[3] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 05期

关键词：

D O I：

10.1128/AAC.49.5.2112-2115.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Chromosomal beta-lactamase genes (bla(KLUY)) from six Kluyvera georgiana strains isolated in Guyana were cloned and expressed in Escherichia coli. KLUY-1 exhibited 100% amino acid identity with the extended-spectrum beta-lactamase CTX-M-14. We also show that a 2.7-kb Kluyvera chromosomal region exhibits 99% nucleotide identity to a portion of In60 that includes bla(CTX-M-9).

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页码：2112 / 2115

页数：4

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