Chlorosulfolipids: Structure, synthesis, and biological relevance

被引：64

作者：

Bedke, D. Karl ^{[1
]}

Vanderwal, Christopher D. ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

来源：

NATURAL PRODUCT REPORTS | 2011年 / 28卷 / 01期

关键词：

CHRYSOPHYTE POTERIOOCHROMONAS-MALHAMENSIS; OCHROMONAS-DANICA; ABSOLUTE-CONFIGURATION; COUPLING-CONSTANTS; FLAGELLAR MEMBRANE; ADRIATIC MUSSELS; IN-VIVO; BIOSYNTHESIS; STEREOCHEMISTRY; CHLORINATION;

D O I：

10.1039/c0np00044b

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chlorosulfolipids have been isolated from freshwater algae and from toxic mussels. They appear to have a structural role in algal membranes and have been implicated in Diarrhetic Shellfish Poisoning. Further fascinating aspects of these compounds include their stereochemically complex polychlorinated structures and the resulting strong conformational biases, and their poorly understood (yet surely compelling) biosynthesis. Discussions of each of these topics and of efforts in structural and stereochemical elucidation and synthesis are the subject of this Highlight.

引用

页码：15 / 25

页数：11

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