Synthesis of 4-substituted tetrahydropyridines by cross-coupling of enol phosphates

被引：66

作者：

Larsen, US

Martiny, L

Begtrup, M ^{[1
]}

机构：

[1] Danish Univ Pharmaceut Sci, Dept Med Chem, DK-2100 Copenhagen, Denmark

[2] Novo Nordisk AS, Isotope Chem, DK-2760 Malov, Denmark

[3] Riso Natl Lab, Radiat Res Dept, DK-4000 Roskilde, Denmark

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 24期

关键词：

D O I：

10.1016/j.tetlet.2005.03.203

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enol phosphates, synthesized from 4-piperidone, react by palladium catalyzed cross-coupling with arylboronic acids and by iron and palladium catalyzed cross-coupling with Grignard reagents to give 4-substituted tetrahydropyridines. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：4261 / 4263

页数：3

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