Solvent-free Mukaiyama aldol reaction of O-silyl dienolates catalyzed by benzoic acid

被引：11

作者：

Acocella, MR ^{[1
]}

Massa, A ^{[1
]}

Palombi, L ^{[1
]}

Villano, R ^{[1
]}

Scettri, A ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, Salerno, Italy

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 36期

关键词：

aldol reaction; molecular sieves; silica gel; silyl dienolates;

D O I：

10.1016/j.tetlet.2005.06.152

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The vinylogous aldol reaction of O-silyl dienolates deriving from 2,2-dimethyl-[1,3]-dioxin-4-ones proceeds in moderate to excellent yields in the presence of catalytic amounts of PhCOOH under solvent-free conditions. Modest to good yields can be obtained by using silica gel or 3 A molecular sieves as heterogeneous catalysts. (c) 2005 Elsevier Ltd. All rights reserved.

引用

收藏

页码：6141 / 6144

页数：4

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