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Functional diversity of helper T lymphocytes

被引：3691
作者：
Abbas, AK
Murphy, KM
Sher, A
机构：
[1] HARVARD UNIV, SCH MED, BOSTON, MA 02115 USA
[2] WASHINGTON UNIV, SCH MED, DEPT PATHOL, ST LOUIS, MO 63110 USA
[3] NIAID, NIH, PARASIT DIS LAB, IMMUNOBIOL SECT, BETHESDA, MD 20892 USA
来源：
NATURE | 1996年 / 383卷 / 6603期
关键词：
D O I：
10.1038/383787a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The existence of subsets of CD4(+) helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity of normal and pathological immune responses. Defining the cellular and molecular mechanisms of helper-T-cell differentiation should lead to rational strategies for manipulating immune responses for prophylaxis and therapy.
引用
收藏
页码：787 / 793
页数：7
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