学术探索
学术期刊
新闻热点
数据分析
智能评审

Dendrimers: a new class of nanoscopic containers and delivery devices

被引：332
作者：
Aulenta, F
Hayes, W [1 ]
Rannard, S
机构：
[1] Univ Reading, Sch Chem, Reading RG6 6AH, Berks, England
[2] Unilever Res Labs, Wirral CH63 3JW, Merseyside, England
来源：
EUROPEAN POLYMER JOURNAL | 2003年 / 39卷 / 09期
关键词：
dendrimer; hyperbranched polymer; drug delivery devices; host-guest chemistries;
D O I：
10.1016/S0014-3057(03)00100-9
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Dendrimers and hyperbranched polymers are a relatively new class of materials with unique molecular architectures and dimensions in comparison to traditional linear polymers. This review details recent notable advances in the application of these new polymers in terms of the development of new polymeric delivery systems. Although comparatively young, the developing field of hyperbranched drug delivery devices is a rapidly maturing area and the key discoveries in drug-conjugate systems amongst others are highlighted. As a consequence of their ideal hyperbranched architectures, the utilisation of host-guest chemistries in dendrimers has been included within the scope of this review. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1741 / 1771
页数：31
相关论文
共 141 条
  • [81] Dynamics of Bengal Rose encapsulated in the Meijer dendrimer box
    Miklis, P
    Cagin, T
    Goddard, WA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (32) : 7458 - 7462
  • [82] PHOTOINDUCED ELECTRON-TRANSFER REACTIONS TO PROBE THE STRUCTURE OF STARBURST DENDRIMERS
    MORENOBONDI, MC
    ORELLANA, G
    TURRO, NJ
    TOMALIA, DA
    [J]. MACROMOLECULES, 1990, 23 (03) : 910 - 912
  • [83] SYNTHESIS, METAL-BINDING PROPERTIES AND POLYPEPTIDE SOLUBILIZATION OF CROWNED ARBOROLS
    NAGASAKI, T
    KIMURA, O
    UKON, M
    HAMACHI, I
    SHINKAI, S
    ARIMORI, S
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1994, (01): : 75 - 81
  • [84] STRATEGIES FOR COVALENT ATTACHMENT OF DOXORUBICIN TO POLY(PEG-LYS), A NEW WATER-SOLUBLE POLY(ETHER URETHANE)
    NATHAN, A
    ZALIPSKY, S
    KOHN, J
    [J]. JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 1994, 9 (03) : 239 - 251
  • [85] COPOLYMERS OF LYSINE AND POLYETHYLENE-GLYCOL - A NEW FAMILY OF FUNCTIONALIZED DRUG CARRIERS
    NATHAN, A
    ZALIPSKY, S
    ERTEL, SI
    AGATHOS, SN
    YARMUSH, ML
    KOHN, J
    [J]. BIOCONJUGATE CHEMISTRY, 1993, 4 (01) : 54 - 62
  • [86] STARBURST DENDRIMERS .5. MOLECULAR SHAPE CONTROL
    NAYLOR, AM
    GODDARD, WA
    KIEFER, GE
    TOMALIA, DA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (06) : 2339 - 2341
  • [87] Approaches towards specifically functionalized cascade macromolecules: Dendrimers with incorporated metal binding sites and their palladium(II) and copper(II) complexes
    Newkome, GR
    Gross, J
    Moorefield, CN
    Woosley, BD
    [J]. CHEMICAL COMMUNICATIONS, 1997, (06) : 515 - 516
  • [88] CHEMISTRY OF MICELLES .13. UNIMOLECULAR MICELLES
    NEWKOME, GR
    MOOREFIELD, CN
    BAKER, GR
    SAUNDERS, MJ
    GROSSMAN, SH
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1991, 30 (09): : 1178 - 1180
  • [89] CHEMISTRY OF MICELLES .11. ALKANE CASCADE POLYMERS POSSESSING MICELLAR TOPOLOGY - MICELLANOIC ACID-DERIVATIVES
    NEWKOME, GR
    MOOREFIELD, CN
    BAKER, GR
    JOHNSON, AL
    BEHERA, RK
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1991, 30 (09): : 1176 - 1178
  • [90] NIIDOME T, 2000, PEP SCI, P201
45678910111213