Disposition of polyoxyethylated excipients in humans: Implications for drug safety and formulation approaches

被引：12

作者：

ten Tije, AJ ^{[1
]}

Loos, WJ

Verweij, J

Baker, SD

Dinh, K

Figg, WD

Sparreboom, A

机构：

[1] Erasmus MC Daniel Hoed Canc Ctr, Dept Med Oncol, Rotterdam, Netherlands

[2] Sidney Kimmel Comprehens Canc Ctr, Div Expt Therapeut, Baltimore, MD USA

[3] Natl Canc Inst, Bethesda, MD USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2003年 / 74卷 / 05期

关键词：

D O I：

10.1016/j.clpt.2003.08.004

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：509 / 510

页数：2

共 10 条

[1] Pharmaceutical excipient development: The need for preclinical guidance [J].

Baldrick, P .

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2000, 32 (02) :210-218

[2] Clinical pharmacokinetics of unbound docetaxel: Role of polysorbate 80 and serum proteins [J].

Loos, WJ ;

Baker, SD ;

Verweij, J ;

Boonstra, JG ;

Sparreboom, A .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2003, 74 (04) :364-371

[3] Quantitation of Cremophor EL in human plasma samples using a colorimetric dye-binding microassay [J].

Sparreboom, A ;

Loos, WJ ;

Verweij, J ;

de Vos, AI ;

van der Burg, MEL ;

Stoter, G ;

Nooter, K .

ANALYTICAL BIOCHEMISTRY, 1998, 255 (02) :171-175

[4]

Sparreboom A, 1998, CLIN CANCER RES, V4, P1937

[5] Determination of the docetaxel vehicle, polysorbate 80, in patient samples by liquid chromatography-tandem mass spectrometry [J].

Sparreboom, A ;

Zhao, M ;

Brahmer, JR ;

Verweij, J ;

Baker, SD .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2002, 773 (02) :183-190

[6]

Szebeni J, 2001, CRIT REV THER DRUG, V18, P567

[7] Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40 [J].

Tayrouz, Y ;

Ding, R ;

Burhenne, J ;

Riedel, KD ;

Weiss, J ;

Hoppe-Tichy, T ;

Haefeli, WE ;

Mikus, G .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2003, 73 (05) :397-405

[8] Pharmacological effects of formulation vehicles - Implications for cancer chemotherapy [J].

ten Tije, AJ ;

Verweij, J ;

Loos, WJ ;

Sparreboom, A .

CLINICAL PHARMACOKINETICS, 2003, 42 (07) :665-685

[9] "Inactive" excipients such as Cremophor can affect in vivo drug disposition [J].

Wandel, C ;

Kim, RB ;

Stein, CM .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2003, 73 (05) :394-396

[10]

WINDEBANK AJ, 1994, J PHARMACOL EXP THER, V268, P1051

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