Modeling tissue morphogenesis and cancer in 3D

被引：1386

作者：

Yamada, Kenneth M. ^{[1
]}

Cukierman, Edna

机构：

[1] Natl Inst Hlth, Natl Inst Dental & Craniofacial Res, Lab Cell & Dev Biol, Bethesda, MD 20892 USA

[2] Fox Chase Canc Ctr, Div Basic Sci, Philadelphia, PA 19111 USA

来源：

CELL | 2007年 / 130卷 / 04期

关键词：

D O I：

10.1016/j.cell.2007.08.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three-dimensional ( 3D) in vitro models span the gap between two-dimensional cell cultures and whole-animal systems. By mimicking features of the in vivo environment and taking advantage of the same tools used to study cells in traditional cell culture, 3D models provide unique perspectives on the behavior of stem cells, developing tissues and organs, and tumors. These models may help to accelerate translational research in cancer biology and tissue engineering.

引用

收藏

页码：601 / 610

页数：10

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