Metal-directed assembly of cyclometallopeptides

被引：10

作者：

Constable, EC ^{[1
]}

Housecroft, CE ^{[1
]}

Mundwiler, S ^{[1
]}

机构：

[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland

来源：

DALTON TRANSACTIONS | 2003年 / 11期

关键词：

D O I：

10.1039/b303684g

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An undecapeptide predisposed to cyclisation as a result of the inclusion of a proline residue has been functionalised with tpy metal-binding domains at both the N and C termini, and shown to form a cyclometallopeptide upon reaction with iron(II) salts.

引用

收藏

页码：2112 / 2114

页数：3

相关论文

共 17 条

[1] The fixation of linear versus loop-type peptidic structures by metal coordination:: the coordination chemistry of Val-Val- and Val-Val-Val-bridged dicatechol ligands [J].

Albrecht, M ;

Spiess, O ;

Schneider, M ;

Weis, P .

CHEMICAL COMMUNICATIONS, 2002, (07) :786-787

[2]

[Anonymous], 1995, METALS LIGAND REACTI

[3]

[Anonymous], TOP CURR CHEM

[4] 4′-aminomethyl-2,2′-bipyridyl-4-carboxylic acid (Abc) and related derivatives:: Novel bipyridine amino acids for the solid-phase incorporation of a metal coordination site within a peptide backbone [J].

Bishop, BM ;

McCafferty, DG ;

Erickson, BW .

TETRAHEDRON, 2000, 56 (27) :4629-4638

[5] New approaches to sugar-functionalised 2,2′:6′,2"-terpyridines based upon tetrafluorophenoxy spacers;: crystal and molecular structures of 4′-(tetrafluoro-4-hydroxyphenyl)-2,2′:6′,2"-terpyridine and 4′-(4-methoxytetrafluorophenyl)-2,2′:6′,2"-terpyridine [J].

Constable, EC ;

Kariuki, B ;

Mahmood, A .

POLYHEDRON, 2003, 22 (05) :687-698

[6] Reversible metal-directed assembly of clusters of vesicles [J].

Constable, EC ;

Meier, W ;

Nardin, C ;

Mundwiler, S .

CHEMICAL COMMUNICATIONS, 1999, (16) :1483-1484

[7] Metal-ion control of molecular recognition-sugar-functionalised 2,2′:6′,2"-terpyridines [J].

Constable, EC ;

Mundwiler, S .

POLYHEDRON, 1999, 18 (18) :2433-2444

[8] The first solution stucture of a single α-helical turn.: A pentapeptide α-helix stabilized by a metal clip [J].

Kelso, MJ ;

Hoang, HN ;

Appleton, TG ;

Fairlie, DP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (42) :10488-10489

[9]

Mergler M, 1999, CHIMIA, V53, P29

[10] Synthesis of two covalently linked bis(2,2′:6′,2"-terpyridine) (terpy) chelating ligands with different length spacers, comparison of the crystal structures of their mononuclear nickel(II) complexes, and kinetic and mechanistic studies of the reaction of one ligand with [Fe(terpy)2]2+ [J].

Priimov, GU ;

Moore, P ;

Maritim, PK ;

Butalanyi, PK ;

Alcock, NW .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 2000, (04) :445-449