Quantitative CARS Molecular Fingerprinting of Single Living Cells with the Use of the Maximum Entropy Method

被引:94
作者
Okuno, Masanari [1 ]
Kano, Hideaki [1 ]
Leproux, Philippe [3 ]
Couderc, Vincent [3 ]
Day, James P. R. [4 ]
Bonn, Mischa [4 ]
Hamaguchi, Hiro-o [1 ,2 ]
机构
[1] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan
[2] Natl Chiao Tung Univ, Inst Mol Sci, Hsinchu 300, Taiwan
[3] CNRS, UMR, Inst Rech XLIM, F-87060 Limoges, France
[4] FOM Inst Atom & Mol Phys, NL-1098 XG Amsterdam, Netherlands
基金
日本科学技术振兴机构;
关键词
CARS (coherent anti-Stokes Raman scattering); time-resolved spectroscopy; vibrational spectroscopy; STOKES-RAMAN SCATTERING; SPECTROSCOPIC SIGNATURE; YEAST-CELLS; COHERENT; MICROSCOPY; SPECTRA; MICROSPECTROSCOPY; LIFE;
D O I
10.1002/anie.201001560
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Fast CARS: The cell-death process was observed in real time at the subcellular level by coherent anti-Stokes Raman microspectroscopy, an extension of antiStokes Raman scattering (CARS) microscopy. Changes in the chemical contrast during the dying process can be clearly resolved (see picture). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:6773 / 6777
页数:5
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