Clickable polymersomes

被引:137
作者
Opsteen, Joost A. [1 ]
Brinkhuis, Rene P. [1 ]
Teeuwen, Rosalie L. M. [1 ]
Loewik, Dennis W. P. M. [1 ]
van Hest, Jan C. M. [1 ]
机构
[1] Radboud Univ Nijmegen, Inst Mol & Mat, Dept Organ Chem, NL-6525 ED Nijmegen, Netherlands
关键词
D O I
10.1039/b704568a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Polymersomes, composed of amphiphilic polystyrene- block-poly(acrylic acid) (PS-b-PAA), with the periphery being covered with azide groups, were used for further functionalization using "click'' chemistry.
引用
收藏
页码:3136 / 3138
页数:3
相关论文
共 32 条
[1]   Vesicles and liposomes:: A self-assembly principle beyond lipids [J].
Antonietti, M ;
Förster, S .
ADVANCED MATERIALS, 2003, 15 (16) :1323-1333
[2]   Multifunctional polymeric nanoparticles from diverse bioactive agents [J].
Bertin, PA ;
Gibbs, JM ;
Shen, CKF ;
Thaxton, CS ;
Russin, WA ;
Mirkin, CA ;
Nguyen, ST .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (13) :4168-4169
[3]   Polystyrene-b-poly(acrylic acid) vesicle size control using solution properties and hydrophilic block length [J].
Choucair, A ;
Lavigueur, C ;
Eisenberg, A .
LANGMUIR, 2004, 20 (10) :3894-3900
[4]   Synthesis of azido end-functionalized polyacrylates via atom transfer radical polymerization [J].
Coessens, V ;
Nakagawa, Y ;
Matyjaszewski, K .
POLYMER BULLETIN, 1998, 40 (2-3) :135-142
[5]  
Davis KA, 2000, J POLYM SCI POL CHEM, V38, P2274, DOI 10.1002/(SICI)1099-0518(20000615)38:12<2274::AID-POLA170>3.0.CO
[6]  
2-I
[7]   Site-specific PEGylation of proteins containing unnatural amino acids [J].
Deiters, A ;
Cropp, TA ;
Summerer, D ;
Mukherji, M ;
Schultz, PG .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (23) :5743-5745
[8]   Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3+2] dipolar cycloaddition reaction [J].
Dirks, AJT ;
van Berkel, SS ;
Hatzakis, NS ;
Opsteen, JA ;
van Delft, FL ;
Cornelissen, JJLM ;
Rowan, AE ;
van Hest, JCM ;
Rutjes, FPJT ;
Nolte, RJM .
CHEMICAL COMMUNICATIONS, 2005, (33) :4172-4174
[9]   Polymer vesicles [J].
Discher, DE ;
Eisenberg, A .
SCIENCE, 2002, 297 (5583) :967-973
[10]   The dawning era of polymer therapeutics [J].
Duncan, R .
NATURE REVIEWS DRUG DISCOVERY, 2003, 2 (05) :347-360