Novel chiral sulfur-containing ferrocenyl ligands for palladium-catalyzed asymmetric allylic substitution

被引：32

作者：

Nakamura, S ^{[1
]}

Fukuzumi, T ^{[1
]}

Toru, T ^{[1
]}

机构：

[1] Nagoya Inst Technol, Dept Appl Chem, Showa Ku, Nagoya, Aichi 4668555, Japan

来源：

CHIRALITY | 2004年 / 16卷 / 01期

关键词：

allylic substitution; ferrocene; enantioselective reaction; sulfoxide; P; S-bidentate ligands;

D O I：

10.1002/chir.10300

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

New chiral ferrocenyl ligands having chiral sulfinyl and phosphinyl groups were prepared. The palladium-catalyzed allylic substitution reaction using these chiral ligands showed good enantioselectivity. The mechanism for the asymmetric reaction is proposed on the basis of the stereochemical outcome. (C) 2003 Wiley-Liss, Inc.

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页码：10 / 12

页数：3

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