Regio selectivity in nickel(0)/phosphine catalyzed cycloadditions of alkynes and isocyanates

被引：36

作者：

Duong, HA ^{[1
]}

Louie, J ^{[1
]}

机构：

[1] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2005年 / 690卷 / 23期

基金：

美国国家科学基金会;

关键词：

nickel; phosphine; catalyst; isocyanates; alkynes; pyridones; cycloaddition; regioselectivity;

D O I：

10.1016/j.jorganchem.2005.03.027

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The regioselectivity of Ni(0)-catalyzed cycloadditions of various isocyanates and asymmetrical alkynes to afford pyridones was explored. The use of PEt3 provided, in most cases, two of the four possible pyridone regioisomers in high overall yields. Mechanistic rationale for the product distribution is provided. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：5098 / 5104

页数：7

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