Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy

被引：163

作者：

Ferrara, Napoleone ^{[1
]}

机构：

[1] Genentech Inc, San Francisco, CA USA

来源：

NATURE MEDICINE | 2010年 / 16卷 / 10期

关键词：

ANTI-VEGF ANTIBODY; PERMEABILITY FACTOR; TYROSINE KINASE; EXTRACELLULAR-MATRIX; NUCLEOTIDE-SEQUENCE; TUMOR ANGIOGENESIS; CELLS SECRETE; BLOOD-VESSELS; NEOVASCULARIZATION; RANIBIZUMAB;

D O I：

10.1038/nm1010-1107

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1107 / 1111

页数：5

共 56 条

[21] Vascular endothelial growth factor is essential for corpus luteum angiogenesis [J].

Ferrara, N ;

Chen, H ;

Davis-Smyth, T ;

Gerber, HP ;

Nguyen, TN ;

Peers, D ;

Chisholm, V ;

Hillan, KJ ;

Schwall, RH .

NATURE MEDICINE, 1998, 4 (03) :336-340

[22] Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer [J].

Ferrara, N ;

Hillan, KJ ;

Gerber, HP ;

Novotny, W .

NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (05) :391-400

[23] PITUITARY FOLLICULAR CELLS SECRETE A NOVEL HEPARIN-BINDING GROWTH-FACTOR SPECIFIC FOR VASCULAR ENDOTHELIAL-CELLS [J].

FERRARA, N ;

HENZEL, WJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 161 (02) :851-858

[24] TRANSPORT EPITHELIAL CHARACTERISTICS OF CULTURED BOVINE PITUITARY FOLLICULAR CELLS [J].

FERRARA, N ;

FUJII, DK ;

GOLDSMITH, PC ;

WIDDICOMBE, JH ;

WEINER, RI .

AMERICAN JOURNAL OF PHYSIOLOGY, 1987, 252 (03) :E304-E312

[25] Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene [J].

Ferrara, N ;

CarverMoore, K ;

Chen, H ;

Dowd, M ;

Lu, L ;

OShea, KS ;

PowellBraxton, L ;

Hillan, KJ ;

Moore, MW .

NATURE, 1996, 380 (6573) :439-442

[26] Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration [J].

Ferrara, Napoleone ;

Damico, Lisa ;

Shams, Naveed ;

Lowman, Henry ;

Kim, Robert .

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2006, 26 (08) :859-870

[27] Binding to the Extracellular Matrix and Proteolytic Processing: Two Key Mechanisms Regulating Vascular Endothelial Growth Factor Action [J].

Ferrara, Napoleone .

MOLECULAR BIOLOGY OF THE CELL, 2010, 21 (05) :687-690

[28] Vascular Endothelial Growth Factor [J].

Ferrara, Napoleone .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2009, 29 (06) :789-791

[29]

FERRIS FL, 1984, ARCH OPHTHALMOL-CHIC, V102, P1640

[30]

FOLKMAN J, 1971, NEW ENGL J MED, V285, P1182

← 1 2 3 4 5 6 →