RNA-based silencing strategies in plants

被引:155
作者
Matzke, MA
Matzke, AJM
Pruss, GJ
Vance, VB
机构
[1] Austrian Acad Sci, Inst Mol Biol, A-5020 Salzburg, Austria
[2] Univ S Carolina, Dept Biol Sci, Columbia, SC 29208 USA
关键词
D O I
10.1016/S0959-437X(00)00183-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In plants, double-stranded RNA can silence genes by triggering degradation of homologous RNA in the cytoplasm and by directing methylation of homologous nuclear DNA sequences. Analyses of Arabidopsis mutants and plant viral suppressors of silencing are unraveling RNA-silencing mechanisms, which require common proteins in diverse organisms, and are assessing the role of methylation in transcriptional and posttranscriptional gene silencing.
引用
收藏
页码:221 / 227
页数:7
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