5,10,15-tris(o-aminophenyl) corrole (TAPC) as a versatile synthon for the preparation of corrole-based hemoprotein analogs

被引：40

作者：

Collman, JP ^{[1
]}

Decréau, RA ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 06期

关键词：

D O I：

10.1021/ol048185s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The atropisomers of 5,10,15-tris(o-aminophenyl) corrole (alpha beta alpha, alpha alpha beta, and alpha alpha alpha) are metastable at room temperature as a result of the low rotational barrier of the o-aminophenyl pickets adjacent to the bipyrrole moiety. Atropisomer enrichment of TAPC was required for the preparation of picket fence, triazacyclononane-capped, and trisimidazole-alpha alpha alpha-corroles. A racemic alpha(2)beta model of cis-A(2)B geometry was also obtained by linking two cis anilines with a short strap and inserting an imidazole tail on the opposite face of TAPC.

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页码：975 / 978

页数：4

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