Ene-yne-ene and ene-yne-yne metathesis of norbornene derivatives

被引：16

作者：

Banti, D ^{[1
]}

North, M ^{[1
]}

机构：

[1] Kings Coll London, Dept Chem, London WC2R 2LS, England

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 44期

关键词：

D O I：

10.1016/j.tetlet.2003.09.035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Norbornene derivatives 4 and 5 containing sidechains bearing an internal alkyne and either a terminal alkene or a terminal alkyne were found to undergo a cascade of metathesis reactions when treated with ruthenium based metathesis catalysts to form highly functionalised pentacyclic products. The reactions illustrate an interesting difference in reactivity between Grubbs' catalyst and the second generation catalyst, with the former being more reactive for the early steps of the cascade. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8157 / 8160

页数：4

共 35 条

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[32] Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis [J].