Ring-closing metathesis strategy to P-heterocycles

被引：57

作者：

Hanson, PR ^{[1
]}

Stoianova, DS ^{[1
]}

机构：

[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 17期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(99)00479-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first examples of ring-closing metathesis reactions with allylphosphonamides 1, vinylphosphonamides 2, and vinylphosphonates 8 using the Grubbs ruthenium catalyst 3 are described. These RCM reactions lead to the 6-membered allylphosphonamides 4, the 5-membered vinylphosphonamides 5, and various 5-, 6- and 7-membered phosphonates 9-10. The yield, rate and mode of metathesis in these reactions are sensitive to simple olefin and nitrogen substitution. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：3297 / 3300

页数：4

共 12 条

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