Benzylation of arenes through FeCl3-catalyzed Friedel-Crafts reaction via C-O activation of benzyl ether

被引：50

作者：

Wang, Bi-Qin ^{[1
,2
]}

Xiang, Shi-Kai ^{[1
,2
]}

Sun, Zuo-Peng ^{[1
,2
]}

Guan, Bing-Tao ^{[2
]}

Hu, Ping ^{[1
]}

Zhao, Ke-Qing ^{[1
]}

Shi, Zhang-Jie ^{[2
]}

机构：

[1] Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu 610066, Sichuan, Peoples R China

[2] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 27期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetlet.2008.04.117

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various benzyl ethers were converted to benzyl arenes via a FeCl3-catalyzed Friedel-Crafts alkylation reaction under mild condition in good yields. This method also offered a simple and practical approach to synthesize di- or tri-aryl methanes and aryl heteroaryl methanes through the activation of C-O bonds. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：4310 / 4312

页数：3

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