The mitochondrial proteom: From inventory to function

被引:105
作者
Meisinger, Chris [1 ]
Sickmann, Albert [2 ]
Pfanner, Nikolaus [1 ]
机构
[1] Univ Freiburg, ZBMZ, Inst Biochem & Mol Biol, D-79104 Freiburg, Germany
[2] Univ Wurzburg, DFG Res Ctr Expt Biomed, Rudolf Virchow Ctr, D-97078 Wurzburg, Germany
关键词
D O I
10.1016/j.cell.2008.06.043
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mitochondria are central to cellular energetics, metabolism, and signaling. In this issue, Pagliarini et al. (2008) report the largest compendium of mammalian mitochondrial proteins to date. Together with proteomic studies in yeast, this study represents an important step toward the systematic characterization of the mitochondrial proteome and of mitochondrial diseases.
引用
收藏
页码:22 / 24
页数:4
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