Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

被引：27

作者：

Shepherd, Rebecca ^{[1
]}

Forbes, Simon A. ^{[1
]}

Beare, David ^{[1
]}

Bamford, S. ^{[1
]}

Cole, Charlotte G. ^{[1
]}

Ward, Sari ^{[1
]}

Bindal, Nidhi ^{[1
]}

Gunasekaran, Prasad ^{[1
]}

Jia, Mingming ^{[1
]}

Kok, Chai Yin ^{[1
]}

Leung, Kenric ^{[1
]}

Menzies, Andrew ^{[1
]}

Butler, Adam P. ^{[1
]}

Teague, Jon W. ^{[1
]}

Campbell, Peter J. ^{[1
]}

Stratton, Michael R. ^{[1
]}

Futreal, P. Andrew ^{[1
]}

机构：

[1] Wellcome Trust Sanger Inst, Canc Genome Project, Hinxton CB10 1SA, Cambs, England

来源：

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION | 2011年

基金：

英国惠康基金;

关键词：

SENSITIVITY; PATHWAYS;

D O I：

10.1093/database/bar018

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Catalogue of Somatic Mutations in Cancer (COSMIC) (http://www.sanger.ac.uk/cosmic) is a publicly available resource providing information on somatic mutations implicated in human cancer. Release v51 (January 2011) includes data from just over 19 000 genes, 161 787 coding mutations and 5573 gene fusions, described in more than 577 000 tumour samples. COSMICMart (COSMIC BioMart) provides a flexible way to mine these data and combine somatic mutations with other biological relevant data sets. This article describes the data available in COSMIC along with examples of how to successfully mine and integrate data sets using COSMICMart.

引用

页数：6

共 19 条

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