Sentinel lymph node mapping in gynecologic malignancies

被引:16
作者
Loar, P. V. [1 ]
Reynolds, R. K., III [1 ]
机构
[1] Univ Michigan, Dept Obstet & Gynecol, Div Gynecol Oncol, Ann Arbor, MI 48109 USA
关键词
sentinel node; Gynecologic oncology; vulvar carcinoma; cervical carcinoma; endometrial carcinoma;
D O I
10.1016/j.ijgo.2007.06.001
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Lymph node status is the most important prognostic factor for women with vulvar, cervical and endometrial carcinoma and complete lymph node dissection has historically been an integral part of the surgical treatment of these diseases. Lymphadenectomy can be morbid for patients, who may experience wound breakdown, lymphocyst formation or chronic lymphedema, among other problems. Sentinel lymph node mapping is a newer technology that allows selective removal of the first node draining a tumor thereby allowing a potentially less aggressive procedure to be performed. Sentinel node mapping is well accepted for the management of breast carcinoma and cutaneous melanoma, and has resulted in reduced morbidity without adversely affecting survival. Sentinel node mapping is currently being investigated for treatment of gynecologic cancers. Recent studies show promise for incorporating the sentinel node mapping technique for treatment of several gynecologic malignancies. (C) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:69 / 74
页数:6
相关论文
共 40 条
[1]  
Ansink AC, 1999, CANCER, V86, P652, DOI 10.1002/(SICI)1097-0142(19990815)86:4<652::AID-CNCR14>3.0.CO
[2]  
2-R
[3]   Sentinel lymph node biopsy improves staging in early cervical cancer [J].
Bats, Anne-Sophie ;
Clement, Denys ;
Larousserie, Florence ;
Lefrere-Belda, Marie-Aude ;
Faraggi, Marc ;
Froissart, Marc ;
Lecuru, Fabrice .
GYNECOLOGIC ONCOLOGY, 2007, 105 (01) :189-193
[4]   Sentinel lymph node procedure in early vulvar cancer [J].
Boran, N ;
Kayikcioglu, F ;
Kir, M .
GYNECOLOGIC ONCOLOGY, 2003, 90 (02) :492-493
[5]   THE MODIFIED RADICAL VULVECTOMY WITH GROIN DISSECTION - AN 8-YEAR EXPERIENCE [J].
BURRELL, MO ;
FRANKLIN, EW ;
CAMPION, MJ ;
CROZIER, MA ;
STACY, DW .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1988, 159 (03) :715-722
[6]  
CABANAS RM, 1977, CANCER, V39, P456, DOI 10.1002/1097-0142(197702)39:2<456::AID-CNCR2820390214>3.0.CO
[7]  
2-I
[8]  
CREASMAN WT, 1987, CANCER, V60, P2035, DOI 10.1002/1097-0142(19901015)60:8+<2035::AID-CNCR2820601515>3.0.CO
[9]  
2-8
[10]   Modern management of vulvar cancer [J].
de Hullu, JA ;
Oonk, MHM ;
van der Zee, AGJ .
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2004, 16 (01) :65-72