Role of base catalysts upon the Pudovik reaction:: Unexpected synthesis of 1,2-dihydropyridine phosphonate derivatives

被引：28

作者：

Albouy, D

Laspéras, M

Etemad-Moghadam, G

Koenig, M

机构：

[1] Univ Toulouse 3, UMR 5623, F-31062 Toulouse 04, France

[2] ENSM, UMR 5618, Montpellier 5, France

[3] Univ Toulouse 3, UPRESA 5069, F-31062 Toulouse 04, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 12期

关键词：

addition reactions; basic zeolite; hydrotalcite; dihydropyridine phosphonate derivatives; Pudovik reaction;

D O I：

10.1016/S0040-4039(99)00189-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The role of base catalysts (CsNaX zeolite, hydrotalcite, triethylamine and pyridine derivatives) upon the regioselectivity of the Pudovik reaction is studied. The unexpected synthesis of stable I,2-dihydropyridine phosphonate derivatives via a one-pot addition reaction under mild conditions is described. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2311 / 2314

页数：4

共 31 条

[1]

ALBOUY D, 1998, IN PRESS J ORG CHEM

[2]

Polymer-bound 4-benzylsulfonyl-1-triphenylphosphoranylidene-2-butanone as a tool for the solid-phase synthesis of substituted piperidin-4-one derivatives. [J].