Evaluation of the effect of aging on retinal nerve fiber layer thickness measured by optical coherence tomography

被引：123

作者：

Kanamori, A ^{[1
]}

Escano, MFT ^{[1
]}

Eno, A ^{[1
]}

Nakamura, M ^{[1
]}

Maeda, H ^{[1
]}

Seya, R ^{[1
]}

Ishibashi, K ^{[1
]}

Negi, A ^{[1
]}

机构：

[1] Kobe Univ, Grad Sch Med, Div Ophthalmol, Dept Organ Therapeut,Chuo Ku, Kobe, Hyogo 6500017, Japan

来源：

OPHTHALMOLOGICA | 2003年 / 217卷 / 04期

关键词：

optical coherence tomography; retinal nerve fiber layer; age; normal eye;

D O I：

10.1159/000070634

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To evaluate the relationship between age and retinal nerve fiber layer (RNFL) thickness in normal subjects, as measured by optical coherence tomography (OCT). Methods: One hundred and forty-four normal subjects (144 eyes), ranging from 16 to 84 years of age, were enrolled in this cross-sectional study. The RNFL thickness was determined using OCT with three circle scans 3.4 mm in diameter. Results: The average RNFL thickness was inversely correlated with age (r = -0.348, p < 0.001). Analyzing the quadrants as a parameter, RNFL thickness in the superior, temporal and inferior quadrants also decreased with age. Using 30-degree segments, there were significant correlations between age and the RNFL thickness of temporal segments (7-11 o'clock). The average RNFL thickness had the highest correlation among all parameters (r = -0.348, p < 0.001). Regarding nasal quadrant thickness, RNFL ratios (average, superior, temporal and inferior RNFL thickness relative to the nasal quadrant thickness) were not significant-

引用

页码：273 / 278

页数：6

共 32 条

[31] SCANNING LASER POLARIMETRY TO MEASURE THE NERVE-FIBER LAYER OF NORMAL AND GLAUCOMATOUS EYES [J].

WEINREB, RN ;

SHAKIBA, S ;

ZANGWILL, L .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 1995, 119 (05) :627-636

[32] A comparison of optical coherence tomography and retinal nerve fiber layer photography for detection of nerve fiber layer damage in glaucoma [J].

Zangwill, LM ;

Williams, J ;

Berry, CC ;

Knauer, S ;

Weinreb, RN .

OPHTHALMOLOGY, 2000, 107 (07) :1309-1315

← 1 2 3 4 →