Organic-inorganic hybrid materials for efficient enantioseparation using cellulose 3,5-dimethylphenylcarbamate and tetraethyl orthosilicate

被引：34

作者：

Ikai, Tomoyuki ^{[2
]}

Yamamoto, Chiyo ^{[3
]}

Kamigaito, Masami ^{[2
]}

Okamoto, Yoshio ^{[1
]}

机构：

[1] Nagoya Univ, EcoTopia Sci Inst, Chikusa Ku, Nagoya, Aichi 4648603, Japan

[2] Nagoya Univ, Grad Sch Engn, Dept Appl Chem, Chikusa Ku, Nagoya, Aichi 4648603, Japan

[3] Suzuka Natl Coll Technol, Shiroko, Suzuka 5100294, Japan

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2008年 / 3卷 / 8-9期

关键词：

chiral packing material; chiral resolution; organic-inorganic hybrid composites; silicon; sol-gel processes;

D O I：

10.1002/asia.200800022

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The hybrid bead-type chiral packing material (CPM) for preparative enantioseparation has been prepared from the cellulose 3,5-dimethylphenylcarbamate containing a small number of 3-(triethoxysily)propyl groups in the presence of tetraethyl orthosilicate, by a sol-gel reaction in an aqueous surfactant solution. The obtained hybrid bead-type CPM was packed into a column and evaluated by high-performance liquid chromatography. When compared with the commercially available Chiralpak IB, which is prepared by the immobilization of cellulose 3,5-dimethylphenylcarbamate on silica gel, the hybrid bead-type CPM was shown to exhibit a similar chiral recognition and possess a higher loading capacity.

引用

页码：1494 / 1499

页数：6

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