Streptomycin-dependent exhibition of cytokine-inducing activity in streptomycin-dependent Mycobacterium tuberculosis strain 18b

被引：4

作者：

Fukasawa, Y

Kawamura, I

Uchiyama, R

Yamamoto, K

Kaku, T

Tominaga, T

Nomura, T

Ichiyama, S

Ezaki, T

Mitsuyama, M

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Microbiol, Sakyo Ku, Kyoto 6068501, Japan

[2] Kyoto Univ, Grad Sch Med, Dept Clin Lab Med, Kyoto 6068501, Japan

[3] Gifu Univ, Grad Sch Med, Dept Microbiol Regenerat & Adv Med Sci, Gifu, Japan

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 10期

关键词：

D O I：

10.1128/IAI.73.10.7051-7055.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Peritoneal exudate cells of mice were stimulated with a streptomycin-dependent Mycobacterium tuberculosis strain, 18b. Gamma interferon production by natural killer cells depending on interleukin-12 and interleukin-18 was induced only in the presence of a high dose of streptomycin. This study suggested the requirement of active bacterial metabolism for this host response.

引用

页码：7051 / 7055

页数：5

共 27 条

[21] Toll-like receptor pathways in the immune responses to mycobacteria [J].