Dendritic cells, Fcγ receptors, and Toll- like receptors:: potential allies in the battle against rheumatoid arthritis

被引:24
作者
Radstake, TRDJ
van Lieshout, AWT
van Riel, PLCM
van den Berg, WB
Adema, GJ
机构
[1] Univ Nijmegen, Med Ctr, Dept Rheumatol, NL-6500 HB Nijmegen, Netherlands
[2] Univ Nijmegen, Med Ctr, Dept Tumor Immunol Lab, NL-6500 HB Nijmegen, Netherlands
关键词
D O I
10.1136/ard.2004.033779
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recent findings suggest an important role for Fc gamma receptors and Toll-like receptors expressed by dendritic cells ( DC) in the pathogenesis of rheumatoid arthritis ( RA). Possibly, DC behaviour might be tuned to counteract the misbalanced immune system in RA. Understanding the precise mechanisms that determine the skewed immune response in RA may provide new clues for the therapeutic use of DC in RA.
引用
收藏
页码:1532 / 1538
页数:7
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