Frigocyclinone, a novel angucyclinone antibiotic produced by a Streptomyces griseus strain from Antarctica

被引：59

作者：

Bruntner, C

Binder, T

Pathom-aree, W

Goodfellow, M

Bull, AT

Potterat, O

Puder, C

Hörer, S

Schmid, A

Bolek, W

Wagner, K

Mihm, G

Fiedler, HP

机构：

[1] Univ Tubingen, Inst Mikrobiol, D-72076 Tubingen, Germany

[2] Univ Newcastle Upon Tyne, Sch Biol, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[3] Univ Kent, Res Sch Biosci, Canterbury CT2 7NJ, Kent, England

[4] Boehringer Ingelheim Pharma GmbH & Co KG, D-88397 Biberach, Germany

来源：

JOURNAL OF ANTIBIOTICS | 2005年 / 58卷 / 05期

关键词：

angucyclinone; screening; antibacterial; antibiotic; Streptomyces griseus;

D O I：

10.1038/ja.2005.43

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new angucyclinone antibiotic, frigocyclinone, was isolated from Streptomyces griseus strain NTK97, consisting of a tetrangomycin moiety attached through a C-glycosidic linkage with the aminodeoxysugar ossamine. Frigocyclinone showed antibacterial activities against Gram-positive bacteria.

引用

页码：346 / 349

页数：4

共 12 条

[1] H-1 AND C-13 NMR-SPECTRA OF SPIRAMYCIN-I IN ORGANIC-SOLUTIONS AND AQUEOUS-SOLUTIONS [J].