A new drimane sesquiterpenoid glycoside from the seeds of Antiaris toxicaria

被引：15

作者：

Dong, Wen-Hua ^{[1
,2
]}

Mei, Wen-Li ^{[1
,2
]}

Zhao, You-Xing ^{[1
,2
]}

Zeng, Yan-Bo ^{[1
,2
]}

Wang, Hui ^{[1
,2
]}

Dai, Hao-Fu ^{[1
,2
]}

机构：

[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Trop Crop Biotechnol, Haikou 571101, Peoples R China

[2] Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2011年 / 13卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Antiaris toxicaria; drimane sesquiterpenoid glycoside; 7-drimen-3; 11-diol; 3-O--d-glucopyranoside; anti-MRSA; cytotoxicity; DART POISONS; CARDIAC-GLYCOSIDES; ROOT BARK; LESCH; PROLIFERATION;

D O I：

10.1080/10286020.2011.573479

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A new drimane sesquiterpenoid glycoside, named 7-drimen-3,11-diol 3-O--d-glucopyranoside, was isolated from the 95% EtOH extract of the seeds of Antiaris toxicaria (Pers.) Lesch. The chemical structure was completely elucidated using a combination of 1D and 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analysis. The compound showed inhibitory activities toward methicillin-resistant Staphylococcus aureus (MRSA), chronic myelogenous leukemia (K562), and human hepatoma (SMMC-7721) cell lines.

引用

页码：561 / 565

页数：5

共 20 条

[1]

MICROBIOLOGICAL HYDROXYLATION IN THE DRIMANE SERIES [J].