Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientation

被引:46
作者
Hellebust, Taran Paulsen [1 ]
Tanderup, Kari
Bergstrand, Eva Stabell
Knutsen, Bjorn Helge
Roislien, Jo
Olsen, Dag Rune
机构
[1] Univ Oslo, Rikshosp, Radiumhosp Med Ctr, Dept Med Phys, N-0027 Oslo, Norway
[2] Univ Oslo, Rikshosp, Radiumhosp Med Ctr, Inst Canc Res, N-0027 Oslo, Norway
[3] Univ Oslo, Rikshosp, Radiumhosp Med Ctr, Sect Biostat, N-0027 Oslo, Norway
[4] Univ Oslo, Dept Phys, N-0027 Oslo, Norway
[5] Aarhus Univ Hosp, Dept Oncol, DK-8000 Aarhus, Denmark
关键词
D O I
10.1088/0031-9155/52/16/012
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The purpose of this study is to investigate whether the method of applicator reconstruction and/or the applicator orientation influence the dose calculation to points around the applicator for brachytherapy of cervical cancer with CT-based treatment planning. A phantom, containing a fixed ring applicator set and six lead pellets representing dose points, was used. The phantom was CT scanned with the ring applicator at four different angles related to the image plane. In each scan the applicator was reconstructed by three methods: ( 1) direct reconstruction in each image (DR), ( 2) reconstruction in multiplanar reconstructed images (MPR) and ( 3) library plans, using pre-defined applicator geometry ( LIB). The doses to the lead pellets were calculated. The relative standard deviation (SD) for all reconstruction methods was less than 3.7% in the dose points. The relative SD for the LIB method was significantly lower ( p < 0.05) than for the DR and MPR methods for all but two points. All applicator orientations had similar dose calculation reproducibility. Using library plans for applicator reconstruction gives the most reproducible dose calculation. However, with restrictive guidelines for applicator reconstruction the uncertainties for all methods are low compared to other factors influencing the accuracy of brachytherapy.
引用
收藏
页码:4893 / 4904
页数:12
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