Terbium-sensitized luminescence optosensor for the determination of norfloxacin in biological fluids

被引：47

作者：

Martínez, EJL ^{[1
]}

Reyes, JFG ^{[1
]}

Barrales, PO ^{[1
]}

Díaz, AM ^{[1
]}

机构：

[1] Univ Jaen, Fac Expt Sci, Dept Phys & Analyt Chem, E-23071 Jaen, Spain

来源：

ANALYTICA CHIMICA ACTA | 2005年 / 532卷 / 02期

关键词：

norfloxacin; lanthanide-sensitized luminescence; terbium; urine; serum;

D O I：

10.1016/j.aca.2004.10.066

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The use of a flow through solid phase terbium-sensitized luminescence system is described for the determination of the widely used fluoroquinolone norfloxacin. A chelate between the terbium ion and the analyte is formed online previously to the sample injection into the carrier stream. Then the chelate is transported towards the flow-through cell, where it is retained on a cationic Sephadex resin packed in the cell, developing the corresponding luminescence signal. Afterwards, an ethylenediaminetetraacetic acid solution was used as eluting agent, in order to regenerate the sensing zone. The system has been satisfactorily applied to the determination of norfloxacin in human urine and serum, without the need of a pre-treatment. The response was linear in the range 10-150 ng ml(-1). The detection and quantification limits were 1.5 and 5 ng ml-', respectively and the R.S.D. 1.82%. (c) 2004 Elsevier B.V. All rights reserved.

引用

页码：159 / 164

页数：6

共 26 条

[1] Simultaneous determination of benzoic acid and saccharin in soft drinks by using lanthanide-sensitized luminescence [J].

Aguilar-Caballos, MP ;

Gómez-Hens, A ;

Pérez-Bendito, D .

ANALYST, 1999, 124 (07) :1079-1084

[2] Room temperature phosphorescence optosensor for anthracyclines [J].

Alava-Moreno, F ;

Valencia-González, MJ ;

Díaz-García, ME .

ANALYST, 1998, 123 (01) :151-154

[3] ROOM-TEMPERATURE PHOSPHORESCENCE OPTOSENSOR FOR TETRACYCLINES [J].

ALAVAMORENO, F ;

DIAZGARCIA, ME ;

SANZMEDEL, A .

ANALYTICA CHIMICA ACTA, 1993, 281 (03) :637-644

[4] Chemiluminescence determination of some fluoroquinolone derivatives in pharmaceutical formulations and biological fluids using [Ru(bipy)23+]-Ce(IV) system [J].

Aly, FA ;

Al-Tamimi, SA ;

Alwarthan, AA .

TALANTA, 2001, 53 (04) :885-893

[5] Improved detection of salicylic acids using terbium-sensitized luminescence in aqueous micellar solutions of cetyltrimethylammonium chloride [J].

Arnaud, N ;

Georges, J .

ANALYST, 1999, 124 (07) :1075-1078

[6] Determination of fluoroquinolones in human urine by liquid chromatography coupled to pneumatically assisted electrospray ionization mass spectrometry [J].

Ballesteros, O ;

Toro, I ;

Sanz-Nebot, V ;

Navalón, A ;

Vílchez, JL ;

Barbosa, J .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2003, 798 (01) :137-144

[7] Solid-phase luminescence determination of ciprofloxacin and norfloxacin in biological fluids [J].

Beltyukova, S ;

Teslyuk, O ;

Egorova, A ;

Tselik, E .

JOURNAL OF FLUORESCENCE, 2002, 12 (02) :269-272

[8] DETERMINATION OF SOME QUINOLONES IN TABLETS, HUMAN PLASMA AND URINE BY DIFFERENTIAL-PULSE POLAROGRAPHY [J].

CORTI, P ;

CORBINI, G ;

GRATTERI, P ;

FURLANETTO, S ;

PINZAUTI, S .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1994, 111 (01) :83-87

[9]

Cuenca-Trujillo RM, 2002, J AOAC INT, V85, P1268

[10] FLUORESCENCE REACTION AND COMPLEXATION EQUILIBRIA BETWEEN NORFLOXACIN AND ALUMINUM(III) ION IN CHLORIDE MEDIUM [J].

DJURDJEVIC, PT ;

JELIKICSTANKOV, M ;

STANKOV, D .

ANALYTICA CHIMICA ACTA, 1995, 300 (1-3) :253-259

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