Pathogenesis, diagnosis and treatment of Rasmussen encephalitis - A European consensus statement

被引：408

作者：

Bien, CG

Granata, T

Antozzi, C

Cross, JH

Dulac, O

Kurthen, M

Lassmann, H

Mantegazza, R

Villemure, JG

Spreafico, R

Elger, CE

机构：

[1] Univ Bonn, Dept Epileptol, D-53105 Bonn, Germany

[2] Inst Nazl Neurol C Besta, Milan, Italy

[3] Inst Child Hlth, London, England

[4] Great Ormond St Hosp Sick Children, London WC1N 3JH, England

[5] Hop Necker Enfants Malad, Serv Malad Metab & Neurol, Paris, France

[6] Med Univ Vienna, Brain Res Inst, Vienna, Austria

[7] CHU Vaudois, CH-1011 Lausanne, Switzerland

来源：

BRAIN | 2005年 / 128卷

关键词：

encephalitis; epilepsy; pathophysiology; diagnostic criteria; therapy;

D O I：

10.1093/brain/awh415

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Rasmussen encephalitis (RE) is a rare but severe immune-mediated brain disorder leading to unilateral hemispheric atrophy, associated progressive neurological dysfunction and intractable seizures. Recent data on the pathogenesis of the disease, its clinical and paraclinical presentation, and therapeutic approaches are summarized. Based on these data, we propose formal diagnostic criteria and a therapeutic pathway for the management of RE patients.

引用

页码：454 / 471

页数：18

共 194 条

[51] MR-monitored remitting-relapsing pattern of cortical involvement in Rasmussen syndrome: Comparative evaluation of serial MR and PET/SPECT features [J].