The question of Plasmodium faliciparum population structure

被引：29

作者：

Awadalla, P ^{[1
]}

Walliker, D

Babiker, H

Mackinnon, M

机构：

[1] Univ Calif Davis, Ctr Populat Biol, Davis, CA 95616 USA

[2] Univ Calif Davis, Sect Evolut & Ecol, Davis, CA 95616 USA

[3] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

TRENDS IN PARASITOLOGY | 2001年 / 17卷 / 08期

关键词：

D O I：

10.1016/S1471-4922(01)02034-7

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Understanding how genetic variation in malaria parasites is structured across populations has benefits for researchers interested in finding loci that affect the ability of the parasite to resist host immunity or drugs. In a recent paper, Tim Anderson and colleagues have provided a broad-scale analysis of Plasmodium falciparum population structure. Their results provide an indication of the feasibility of using population-genetic and genetic-mapping approaches to pinpoint selected loci, in addition to reconciling some previously disparate views of population structure in malaria.

引用

页码：351 / 353

页数：3

共 19 条

[1] Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum
Anderson, TJC
Haubold, B
Williams, JT
Estrada-Franco, JG
Richardson, L
Mollinedo, R
Bockarie, M
Mokili, J
Mharakurwa, S
French, N
Whitworth, J
Velez, ID
Brockman, AH
Nosten, F
Ferreira, MU
Day, KP
[J]. MOLECULAR BIOLOGY AND EVOLUTION, 2000, 17 (10) : 1467 - 1482
[2] Current views on the population structure of Plasmodium falciparum: Implications for control
Babiker, HA
Walliker, D
[J]. PARASITOLOGY TODAY, 1997, 13 (07): : 262 - 267
[3] Measures of divergence between populations and the effect of forces that reduce variability
Charlesworth, B
[J]. MOLECULAR BIOLOGY AND EVOLUTION, 1998, 15 (05) : 538 - 543
[4] A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses
Conway, DJ
Cavanagh, DR
Tanabe, K
Roper, C
Mikes, ZS
Sakihama, N
Bojang, KA
Oduola, AMJ
Kremsner, PG
Arnot, DE
Greenwood, BM
McBride, JS
[J]. NATURE MEDICINE, 2000, 6 (06) : 689 - 692
[5] Natural selection on polymorphic malaria antigens and the search for a vaccine
Conway, DJ
[J]. PARASITOLOGY TODAY, 1997, 13 (01): : 26 - 29
[6] High recombination rate in natural populations of Plasmodium falciparum
Conway, DJ
Roper, C
Oduola, AMJ
Arnot, DE
Kremsner, PG
Grobusch, MP
Curtis, CF
Greenwood, BM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (08) : 4506 - 4511
[7] Origin of Plasmodium falciparum malaria is traced by mitochondrial DNA
Conway, DJ
Fanello, C
Lloyd, JM
Al-Joubori, BMAS
Baloch, AH
Somanath, SD
Roper, C
Oduola, AMJ
Mulder, B
Povoa, MM
Singh, B
Thomas, AW
[J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2000, 111 (01) : 163 - 171
[8] Geographical distribution of a variant epitope of Pfs48/45, a Plasmodium falciparum transmission-blocking vaccine candidate
Drakeley, CJ
Duraisingh, MT
Povoa, M
Conway, DJ
Targett, GAT
Baker, DA
[J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1996, 81 (02) : 253 - 257
[9] Multigenic drug resistance among inbred malaria parasites
Dye, C
Williams, BG
[J]. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1997, 264 (1378) : 61 - 67
[10] Escalante AA, 1998, GENETICS, V149, P189

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