Targeted therapies in lung cancer

被引:35
作者
Besse, B.
Ropert, S.
Soria, J. C.
机构
[1] Inst Gustave Roussy, Dept Med, F-94800 Villejuif, France
[2] Hop Cochin, GHU Ouest, Dept Oncol, F-75674 Paris, France
关键词
GROWTH-FACTOR-RECEPTOR; PHASE-II TRIAL; PROTEIN-KINASE-C; TRANSFERASE INHIBITOR R115777; MATRIX-METALLOPROTEINASE; TYROSINE KINASE; ANTISENSE OLIGONUCLEOTIDE; ACTIVATING MUTATIONS; UNTREATED PATIENTS; IMPROVED SURVIVAL;
D O I
10.1093/annonc/mdm308
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:135 / 142
页数:8
相关论文
共 91 条
[21]   Sorafenib in advanced clear-cell renal-cell carcinoma [J].
Escudier, Bernard ;
Eisen, Tim ;
Stadler, Walter M. ;
Szczylik, Cezary ;
Oudard, Stephane ;
Siebels, Michael ;
Negrier, Sylvie ;
Chevreau, Christine ;
Solska, Ewa ;
Desai, Apurva A. ;
Rolland, Frederic ;
Demkow, Tomasz ;
Hutson, Thomas E. ;
Gore, Martin ;
Freeman, Scott ;
Schwartz, Brian ;
Shan, Minghua ;
Simantov, Ronit ;
Bukowski, Ronald M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (02) :125-134
[22]   Randomized phase II study of bortezomib alone and bortezomib in combination with docetaxel in previously treated advanced non-small-cell lung cancer [J].
Fanucchi, Michael P. ;
Fossella, Frank V. ;
Belt, Robert ;
Natale, Ronald ;
Fidias, Panos ;
Carbone, David P. ;
Govindan, Ramaswamy ;
Raez, Luis E. ;
Robert, Francisco ;
Ribeiro, Maria ;
Akerley, Wallace ;
Kelly, Karen ;
Limentani, Steven A. ;
Crawford, Jeffrey ;
Reimers, Hans-Joachim ;
Axelrod, Rita ;
Kashala, Oscar ;
Sheng, Shihong ;
Schiller, Joan H. .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (31) :5025-5033
[23]   WHAT IS THE EVIDENCE THAT TUMORS ARE ANGIOGENESIS DEPENDENT [J].
FOLKMAN, J .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1990, 82 (01) :4-6
[24]   Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer [J].
Fukuoka, M ;
Yano, S ;
Giaccone, G ;
Tamura, T ;
Nakagawa, K ;
Douillard, JY ;
Nishiwaki, Y ;
Vansteenkiste, J ;
Kudoh, S ;
Rischin, D ;
Eek, R ;
Horai, T ;
Noda, K ;
Takata, I ;
Smit, E ;
Averbuch, S ;
Macleod, A ;
Feyereislova, A ;
Dong, RP ;
Baselga, J .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (12) :2237-2246
[25]   Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A north central cancer treatment group study [J].
Galanis, E ;
Buckner, JC ;
Maurer, MJ ;
Kreisberg, JL ;
Ballman, K ;
Boni, J ;
Peralba, JM ;
Jenkins, RB ;
Dakhil, SR ;
Morton, RF ;
Jaeckle, KA ;
Scheithauer, BW ;
Dancey, J ;
Hidalgo, M ;
Walsh, DJ .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (23) :5294-5304
[26]  
Gatzemeier U, 2004, J CLIN ONCOL, V22, p619S
[27]   Randomized phase II trial of gemcitabine-cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer [J].
Gatzemeier, U ;
Groth, G ;
Butts, C ;
Van Zandwijk, N ;
Shepherd, F ;
Ardizzoni, A ;
Barton, C ;
Ghahramani, P ;
Hirsh, V .
ANNALS OF ONCOLOGY, 2004, 15 (01) :19-27
[28]   Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT1 [J].
Giaccone, G ;
Herbst, RS ;
Manegold, C ;
Scagliotti, G ;
Rosell, R ;
Miller, V ;
Natale, RB ;
Schiller, JH ;
von Pawel, J ;
Pluzanska, A ;
Gatzemeier, M ;
Grous, J ;
Ochs, JS ;
Averbuch, SD ;
Wolf, MK ;
Rennie, P ;
Fandi, A ;
Johnson, DH .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (05) :777-784
[29]   An NCICCTG phase I/pharmacokinetic study of the matrix metalloproteinase and angiogenesis inhibitor BAY 12-9566 in combination with 5-fluorouracil/leucovorin [J].
Goel, R ;
Chouinard, E ;
Stewart, DJ ;
Huan, S ;
Hirte, H ;
Stafford, S ;
Waterfield, B ;
Roach, J ;
Lathia, C ;
Agarwal, V ;
Humphrey, R ;
Walsh, W ;
Matthews, S ;
Seymour, L .
INVESTIGATIONAL NEW DRUGS, 2005, 23 (01) :63-71
[30]   Tissue inhibitor of metalloproteinase 1 is an independent predictor of prognosis in patients with nonsmall cell lung carcinoma who undergo resection with curative intent [J].
Gouyer, V ;
Conti, M ;
Devos, P ;
Zerimech, F ;
Copin, MC ;
Créme, E ;
Wurtz, A ;
Porte, H ;
Huet, G .
CANCER, 2005, 103 (08) :1676-1684