Enantioselective synthesis of (+)-α-vetivone through the Michael reaction of chiral imines

被引：28

作者：

Revial, G

Jabin, I

Pfau, M

机构：

[1] ESPCI, CNRS, ESA 7084, Chim Organ Lab, F-75231 Paris 05, France

[2] Univ Havre, URCOM, Fac Sci & Tech, F-76058 Le Havre, France

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 24期

关键词：

D O I：

10.1016/S0957-4166(00)00481-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(+)-alpha -Vetivone has been synthesised in nine steps. The absolute stereochemistry of the two stereogenic centres is controlled in the same key step involving the stereoselective Michael addition of a chiral imine of 4-isopropylidene-2-methylcyclohexanone to phenyl crotonate. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：4975 / 4983

页数：9

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