p53: Pro-aging or pro-longevity?

被引：39

作者：

de Keizer, Peter L. J. ^{[1
]}

Laberge, Remi-Martin ^{[1
]}

Campisi, Judith ^{[1
,2
]}

机构：

[1] Buck Inst Age Res, Novato, CA 94945 USA

[2] Univ Calif Berkeley, Lawrence Berkeley Lab, Berkeley, CA 94720 USA

来源：

AGING-US | 2010年 / 2卷 / 07期

关键词：

CELLULAR SENESCENCE; INFLAMMATORY NETWORKS; SECRETORY PHENOTYPE; TUMOR SUPPRESSION; MOUSE; CELLS; MICE; TRANSFORMATION; RESISTANT; ONCOGENE;

D O I：

10.18632/aging.100178

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

引用

页码：377 / 379

页数：3

共 30 条

[1]

Reversal of human cellular senescence:: roles of the p53 and p16 pathways [J].

Beauséjour, CM ;

Krtolica, A ;

Galimi, F ;

Narita, M ;

Lowe, SW ;

Yaswen, P ;

Campisi, J .

EMBO JOURNAL, 2003, 22 (16) :4212-4222

[2]

Bruunsgaard H, 2006, DAN MED BULL, V53, P285

[3]

INDUCTION OF THE GROWTH INHIBITOR IGF-BINDING PROTEIN-3 BY P53 [J].

BUCKBINDER, L ;

TALBOTT, R ;

VELASCOMIGUEL, S ;

TAKENAKA, I ;

FAHA, B ;

SEIZINGER, BR ;

KLEY, N .

NATURE, 1995, 377 (6550) :646-649

[4]

Fragile fugue: p53 in aging, cancer and IGF signaling [J].

Campisi, J .

NATURE MEDICINE, 2004, 10 (03) :231-232

[5]

Between Scylla and Charybdis: p53 links tumor suppression and aging [J].

Campisi, J .

MECHANISMS OF AGEING AND DEVELOPMENT, 2002, 123 (06) :567-573

[6]

Cellular senescence: when bad things happen to good cells [J].

Campisi, Judith ;

di Fagagna, Fabrizio d'Adda .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (09) :729-740

[7]

Chipuk JE, 2004, CELL CYCLE, V3, P429

[8]

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression [J].

Coppe, Jean -Philippe ;

Desprez, Pierre-Yves ;

Krtolica, Ana ;

Campisi, Judith .

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2010, 5 :99-118

[9]

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen [J].

Coppe, Jean-Philippe ;

Patil, Christopher K. ;

Rodier, Francis ;

Krtolica, Ana ;

Beausejour, Christian M. ;

Parrinello, Simona ;

Hodgson, J. Graeme ;

Chin, Koei ;

Desprez, Pierre-Yves ;

Campisi, Judith .

PLOS ONE, 2010, 5 (02)

[10]

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor [J].

Coppe, Jean-Philippe ;

Patil, Christopher K. ;

Rodier, Francis ;

Sun, Yu ;

Munoz, Denise P. ;

Goldstein, Joshua ;

Nelson, Peter S. ;

Desprez, Pierre-Yves ;

Campisi, Judith .

PLOS BIOLOGY, 2008, 6 (12) :2853-2868

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