Pro-angiogenic properties of europium(III) hydroxide nanorods

被引:95
作者
Patra, Chitta Ranjan [1 ]
Bhattacharya, Resham [1 ]
Patra, Sujata [1 ]
Vlahakis, Nicholas E. [1 ,2 ]
Gabashvili, Alexandra [3 ,4 ]
Koltypin, Yuri [3 ,4 ]
Gedanken, Aharon [3 ,4 ]
Mukherjee, Priyabrata [1 ,2 ]
Mukhopadhyay, Debabrata [1 ,2 ]
机构
[1] Mayo Clin, Coll Med, Dept Biochem & Mol Biol, Rochester, MN 55905 USA
[2] Mayo Clin, Coll Med, Dept Biomed Engn, Rochester, MN 55905 USA
[3] Bar Ilan Univ, Dept Chem, IL-52900 Ramat Gan, Israel
[4] Bar Ilan Univ, Kanbar Lab Nanomat, Ctr Adv Mat & Nanotechnol, IL-52900 Ramat Gan, Israel
关键词
D O I
10.1002/adma.200701611
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Human umbilical vein endothelial cells (HUVECs) treated with europium(III) hydroxide nanorods (center figure) indicate the internalization of these nanorods to the cytoplasm of the cells. Chick chorioallantoic membrane (CAM) assay of HUVECS treated with the nanorods shows the formation of vascular sprouting, which supports in vivo angiogenesis.
引用
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页码:753 / +
页数:5
相关论文
共 26 条
[11]   ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis [J].
Mavria, G ;
Vercoulen, Y ;
Yeo, M ;
Paterson, H ;
Karasarides, M ;
Marais, R ;
Bird, D ;
Marshall, CJ .
CANCER CELL, 2006, 9 (01) :33-44
[12]   p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts [J].
Milanini, J ;
Viñals, F ;
Pouysségur, J ;
Pagès, G .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (29) :18165-18172
[13]  
Nickoloff SJ, 2006, FASEB J, V20, pA709
[14]   Inorganic phosphate nanorods are a novel fluorescent label in cell biology [J].
Patra C.R. ;
Bhattacharya R. ;
Patra S. ;
Basu S. ;
Mukherjee P. ;
Mukhopadhyay D. .
Journal of Nanobiotechnology, 4 (1)
[15]   Microwave approach for the synthesis of rhabdophane-type lanthanide orthophosphate (Ln = La, Ce, Nd, Sm, Eu, Gd and Tb) nanorods under solvothermal conditions [J].
Patra, CR ;
Alexandra, G ;
Patra, S ;
Jacob, DS ;
Gedanken, A ;
Landau, A ;
Gofer, Y .
NEW JOURNAL OF CHEMISTRY, 2005, 29 (05) :733-739
[16]  
RAJASHEKHAR G, 2007, FASEB J, V706, P8
[17]   Mechanisms of angiogenesis [J].
Risau, W .
NATURE, 1997, 386 (6626) :671-674
[18]  
Roca C, 2003, CANCER RES, V63, P1500
[19]  
SHEAFF RJ, 1998, CELL CYCLE CONTROL, P1
[20]   Reactive oxygen species as mediators of angiogenesis signaling - Role of NAD(P)H oxidase [J].
Ushio-Fukai, M ;
Alexander, RW .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2004, 264 (1-2) :85-97