Sweeping-window arc therapy: an implementation of rotational IMRT with automatic beam-weight calculation

被引:70
作者
Cameron, C [1 ]
机构
[1] Stanford Univ, Ctr Canc, Dept Radiat Oncol, Div Radiat Phys, Stanford, CA 94305 USA
关键词
D O I
10.1088/0031-9155/50/18/006
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Sweeping-window arc therapy (SWAT) is a variation of intensity-modulated radiation therapy (IMRT) with direct aperture optimization (DAO) that is initialized with a leaf sequence of sweeping windows that move back and forth periodically across the target as the gantry rotates. This initial sequence induces modulation in the dose and is assumed to be near enough to a minimum to allow successful optimization, done with simulated annealing, without requiring excessive leaf speeds. Optimal beam weights are calculated analytically, with easy extension to allow for variable beam weights. In this paper SWAT is tested on a phantom model and clinical prostate case. For the phantom, constant and variable beam weights are used. Although further work (in particular, improving the dose model) is required, the results show SWAT to be a feasible approach to generating deliverable dynamic arc treatments that are optimized.
引用
收藏
页码:4317 / 4336
页数:20
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