The oxa-Michael reaction:: from recent developments to applications in natural product synthesis

被引：419

作者：

Nising, Carl F. ^{[1
]}

Braese, Stefan ^{[2
]}

机构：

[1] Bayer Cropsci AG, D-40789 Monheim, Germany

[2] Univ Karlsruhe TH, D-76131 Karlsruhe, Germany

来源：

CHEMICAL SOCIETY REVIEWS | 2008年 / 37卷 / 06期

关键词：

D O I：

10.1039/b718357g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In marked contrast to Michael reactions, oxa-Michael reactions have not been used as standard transformations in organic synthesis until quite recently. This was mainly due to a lack of reactivity and selectivity, although the potential products of such reactions are valuable intermediates. This tutorial review presents recent major advances in the field of oxa-Michael (sometimes called oxo-Michael or oxy-Michael) reactions and applications in the total synthesis of complex natural products.

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页码：1218 / 1228

页数：11

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