Endothelin-Biology and disease

被引：158

作者：

Khimji, Al-Karim ^{[1
]}

Rockey, Don C. ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Div Digest & Liver Dis, Dept Internal Med, Dallas, TX 75390 USA

来源：

CELLULAR SIGNALLING | 2010年 / 22卷 / 11期

关键词：

Endothelin-converting enzyme; Weilbel-Palade bodies; Sarafatoxin; Myofibroblasts; Nitric oxide; Wound healing; CHRONIC HEART-FAILURE; PROTEIN-KINASE-C; CHRONIC-RENAL-FAILURE; SMOOTH-MUSCLE-CELLS; PLACEBO-CONTROLLED TRIAL; PORCINE CORONARY-ARTERY; CONVERTING ENZYME ECE-1; B RECEPTOR EXPRESSION; NITRIC-OXIDE SYNTHASE; BASAL VASCULAR-TONE;

D O I：

10.1016/j.cellsig.2010.05.002

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Endothelins are important mediators of physiological and pathophysiologic processes including cardiovascular disorders, pulmonary disease, renal diseases and many others. Additionally, endothelins are involved in many other important processes such as development, cancer biology, wound healing, and even neurotransmission. Here, we review the cell and molecular biology as well as the prominent pathophysiological aspects of the endothelin system. (C) 2010 Published by Elsevier Inc.

引用

页码：1615 / 1625

页数：11

共 209 条

[51] Modulation of human colon tumor-stromal interactions by the endothelin system [J].

Egidy, G ;

Juillerat-Jeanneret, L ;

Jeannin, JF ;

Korth, P ;

Bosman, FT ;

Pinet, F .

AMERICAN JOURNAL OF PATHOLOGY, 2000, 157 (06) :1863-1874

[52] ENDOTHELINS, PEPTIDES WITH POTENT VASOACTIVE PROPERTIES, ARE PRODUCED BY HUMAN MACROPHAGES [J].

EHRENREICH, H ;

ANDERSON, RW ;

FOX, CH ;

RIECKMANN, P ;

HOFFMAN, GS ;

TRAVIS, WD ;

COLIGAN, JE ;

KEHRL, JH ;

FAUCI, AS .

JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 172 (06) :1741-1748

[53] CELLULAR MECHANISM OF THROMBIN ON ENDOTHELIN-1 BIOSYNTHESIS AND RELEASE IN BOVINE ENDOTHELIAL-CELL [J].

EMORI, T ;

HIRATA, Y ;

IMAI, T ;

OHTA, K ;

KANNO, K ;

EGUCHI, S ;

MARUMO, F .

BIOCHEMICAL PHARMACOLOGY, 1992, 44 (12) :2409-2411

[54] ENDOTHELIN-CONVERTING ENZYME-2 IS A MEMBRANE-BOUND, PHOSPHORAMIDON-SENSITIVE METALLOPROTEASE WITH ACIDIC PH OPTIMUM [J].

EMOTO, N ;

YANAGISAWA, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (25) :15262-15268

[55] CHARACTERIZATION OF ENDOTHELIN RECEPTOR SUBTYPES ON AIRWAY SMOOTH-MUSCLE CELLS [J].

ERGUL, A ;

GLASSBERG, MK ;

WANNER, A ;

PUETT, D .

EXPERIMENTAL LUNG RESEARCH, 1995, 21 (03) :453-468

[56] Renal haemodynamic effects of endothelin-1 and the ETA/ETB antagonist TAK-044 in anaesthetized rabbits [J].

Evans, RG ;

Bergström, G ;

Cotterill, E ;

Anderson, WP .

JOURNAL OF HYPERTENSION, 1998, 16 (12) :1897-1905

[57] Endothelin-1 and angiotensin II receptors in cells from rat hypertrophied heart - Receptor regulation and intracellular Ca2+ modulation [J].

Fareh, J ;

Touyz, RM ;

Schiffrin, EL ;

Thibault, G .

CIRCULATION RESEARCH, 1996, 78 (02) :302-311

[58] Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease [J].

Feng, Hong-Qiang ;

Weymouth, Nate D. ;

Rockey, Don C. .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2009, 297 (01) :G27-G33

[59] Effects of oncological surgery on endothelin-1 secretion in patients with operable gastric cancer [J].

Ferrari-Bravo, A ;

Franciosi, C ;

Lissoni, P ;

Fumagalli, L ;

Uggeri, F .

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2000, 15 (01) :56-57

[60] ENDOTHELIN ACTIVATION OF PHOSPHOLIPASE-D - DUAL MODULATION BY PROTEIN-KINASE-C AND CA2+ [J].

FRIEDLAENDER, MM ;

JAIN, D ;

AHMED, Z ;

HART, D ;

BARNETT, RL ;

NORD, EP .

AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 264 (05) :F845-F853

← 1 2 3 4 5 6 7 8 9 10 →