Novel and general entry into pseudoguaianolides. Formal and enantioselective synthesis of (+)-confertin

被引：18

作者：

Ohtsuka, M ^{[1
]}

Takekawa, Y ^{[1
]}

Shishido, K ^{[1
]}

机构：

[1] Univ Tokushima, Inst Med Resources, Tokushima 7708505, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 32期

关键词：

radicals and radical reactions; terpene and terpenoids; enantiocontrol;

D O I：

10.1016/S0040-4039(98)01180-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and general access to pseudoguaianolide sesquiterpenoids has been developed by employing a diastereoselective acyl radical-mediated 7-endo-trigonal mode of cyclization as a key reaction step. The methodology has successfully been applied to the formal enantioselective synthesis of (+)-confertin. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5803 / 5806

页数：4

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