Highly efficient and precise base editing in discarded human tripronuclear embryos

被引:60
作者
Li, Guanglei [1 ]
Liu, Yajing [2 ]
Zeng, Yanting [1 ]
Li, Jianan [2 ]
Wang, Lijie [2 ]
Yang, Guang [2 ]
Chen, Dunjin [1 ,4 ]
Shang, Xiaoyun [3 ]
Chen, Jia [2 ]
Huang, Xingxu [2 ]
Liu, Jianqiao [1 ]
机构
[1] Guangzhou Med Univ, Dept Reprod Med, Affiliated Hosp 3, Guangzhou 510150, Guangdong, Peoples R China
[2] ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
[3] Third Mil Med Univ, Inst Immunol, PLA, Chongqing 400038, Peoples R China
[4] Guangzhou Med Univ, Affiliated Hosp 3, Key Lab Reprod & Genet, Guangdong Higher Educ Inst,Key Lab Major Obstetri, Guangzhou 510150, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
GENOME; NUCLEASES; CLEAVAGE; ZYGOTES;
D O I
10.1007/s13238-017-0458-7
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:776 / 779
页数:4
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