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A convenient and economical method for the preparation of DIP-Chloride(TM) and its application in the asymmetric reduction of aralkyl ketones
被引:40
作者:
Zhao, MZ
King, AO
Larsen, RD
Verhoeven, TR
Reider, PJ
机构:
[1] Process Research Department, Merck Research Laboratories, Merck and Co. Inc., Rahway, NJ 07065
关键词:
D O I:
10.1016/S0040-4039(97)00440-1
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
A convenient and economical in situ preparation of DIP-Chloride(TM) from NaBH4, BCl3 and alpha-pinene is described. Its application in the asymmetric reduction of representative aralkyl ketones is presented. (C) 1997 Elsevier Science Ltd.
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页码:2641 / 2644
页数:4
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